Research & Publications
The evidence behind the technique
Peer-reviewed prosthetic urology research by Dr. Edward Gheiler, MD, FACS — grouped by the clinical question each paper answers, with a PubMed or DOI identifier on every citation.
Why this page is here
A masterclass is only as good as the reasoning behind each step. Surgeons who come to Miami ask — correctly — why the prep protocol is what it is, why the sizing is done that way, why the reservoir goes where it goes. The honest answer is usually a study, and often one Dr. Edward Gheiler helped write.
So this page is the reading list that sits under the curriculum. Each group below states the question, then the papers that answer it. If a module in the course changed the way you do something, the citation for that change should be here.
The course director
A practice and a research question that are the same thing
Dr. Edward Gheiler, MD, FACS, has spent three decades on one set of questions: what happens to men after an inflatable penile prosthesis goes in, and how the operation can be run so that less goes wrong. More than 8,000 prosthetic-urology cases and roughly 400 implant procedures a year in the greater Miami area sit behind that work, and more than 250 urologists have since trained on the concealed-scar scrotal technique it produced.
He is Clinical Associate Professor and Director of the Prosthetic Urology & Sexual Medicine Fellowship at Nova Southeastern University’s Dr. Kiran C. Patel College of Osteopathic Medicine, and an officer of the Urological Research Network, where he has served as principal investigator on sponsored clinical trials. He completed urology residency at Wayne State University and a urologic oncology fellowship at Harper University Hospital (Detroit Medical Center), is a Fellow of the American College of Surgeons, and has authored more than 65 peer-reviewed publications. His practice is designated a Boston Scientific AMS 700 Center of Excellence.
Lines of inquiry
- Long-term outcomes and quality of life after inflatable penile implantation
- Penile length and glans sensation after prosthetic surgery
- Prosthesis infection — the organisms, the prophylaxis regimens, and the environment around the case
- Revision, salvage, and operating on a pelvis that already contains a device
- Peri-operative pain control in implant surgery
- Surgical education: how implant technique is taught and how quickly it transfers
Selected prosthesis publications
13 peer-reviewed papers, grouped by theme rather than by date. The author name is indexed both as “Gheiler EL” and “Gheiler E”, so a single PubMed query can miss half the record — the full-bibliography link below covers both.
Implant outcomes & quality of life
The counseling numbers you quote before surgery — satisfaction, psychosexual adjustment, and how long a multi-component device actually lasts — come from series like these.
Luna E, Rodriguez D, Barrios D, et al. Evaluation of quality of life after inflatable penile implantation and analysis of factors influencing postsurgery patient satisfaction. J Sex Med. 2022.
Tefilli MV, Dubocq F, Rajpurkar A, et al. Assessment of psychosexual adjustment after insertion of inflatable penile prosthesis. Urology. 1998.
Dubocq F, Tefilli MV, Gheiler EL, et al. Long-term mechanical reliability of multicomponent inflatable penile prosthesis: comparison of device survival. Urology. 1998.
Length & sensation
The two complaints that dominate the first postoperative year. Module V (implant selection and cosmesis) and the sizing steps of the masterclass are built on this work — including what happens to measured length when no standardized cycling protocol is imposed.
Gheiler E, et al. Long-term change in measured penile length after primary inflatable penile prosthesis without a standardized postoperative cycling protocol. J Sex Med. 2026 (in press).
DOI 10.1093/jsxmed/qdag254 (registered; resolves on publication)
Xie D, Nicholas M, Gheiler V, et al. A prospective evaluation of penile measures and glans penis sensory changes after penile prosthetic surgery. Transl Androl Urol. 2017.
Infection: microbiology, prophylaxis, environment
Module I of the curriculum is a protocol, not an opinion. These multicenter studies describe which organisms actually turn up, how the AUA and EAU prophylaxis regimens perform against them, what a second gentamicin dose does, and why geography belongs in the risk conversation.
Gross MS, Vollstedt AJ, Cleves MA, et al. Multicenter investigation on the influence of climate in penile prosthesis infection. Int J Impot Res. 2020.
Xie D, Gheiler V, Lopez I, et al. Experience with prophylactic gentamicin during penile prosthesis surgery: a retrospective comparison of two different doses. J Sex Med. 2017.
Gross MS, Phillips EA, Carrasquillo RJ, et al. Multicenter investigation of the micro-organisms involved in penile prosthesis infection: an analysis of the efficacy of the AUA and EAU guidelines for penile prosthesis prophylaxis. J Sex Med. 2017.
Revision & salvage
The reoperative cases in the case library have a paper behind them: getting a device out, deactivating one that cannot come out, recognizing a malfunction that is not the device at all, and operating on a pelvis that already contains a prosthesis.
Luna E, Garden B, Rodriguez D, et al. Permanent deactivation of inflatable penile prosthesis via puncture. Urology. 2022.
Narain V, Gheiler EL, Tiguert R, et al. Cavernoscopy as an aid in the removal of a penile prosthesis. J Urol. 1999.
Tiguert R, Hurley PM, Gheiler EL, et al. Treatment outcome after radical prostatectomy is not adversely affected by a pre-existing penile prosthesis. Urology. 1998.
Tiguert R, Tefilli MV, Gheiler E, et al. Inguinal hernia as a rare cause of penile prosthesis malfunction: a report of two cases. Urol Int. 1998.
Peri-operative pain control
Two local-anesthetic agents for the dorsal penile nerve and penile ring block, compared prospectively against a no-block control. It is why a block is part of the technique at all, and why the choice of agent is taught rather than assumed.
Xie D, Nicholson M, Azaiza M, et al. Effect of operative local anesthesia on postoperative pain outcomes of inflatable penile prosthesis: prospective comparison of two medications. Int J Impot Res. 2018.
Author identifiers & the full record
The list above is a selection limited to prosthetic urology. The complete bibliography — including the urologic oncology and reconstruction work — is on PubMed and in the curriculum vitae published on this site.
- ORCID
- 0009-0003-6992-4455
- Scopus Author ID
- 7004649795
- Research profile
- Urological Research Network
For fellowship applicants
What a research record means for a fellow
The Prosthetic Urology & Sexual Medicine Fellowship at NSU’s Dr. Kiran C. Patel College of Osteopathic Medicine is directed by Dr. Edward Gheiler and listed on SMSNA Select, where it appears as a fellowship in prosthetic urology and men’s health. A fellow joins an operative practice that is also an active research site: the prospective series, the multicenter infection collaborations, and the anesthesia comparison above were all run alongside the same clinic and OR schedule a fellow works in. Projects come with a denominator, and questions raised in the OR have somewhere to go.
Program details, eligibility, and how to apply are on the fellowship section of the home page and the SMSNA Select listing.